A global multi-institutional Typhoid fever genomic surveillance network to improve global public health outcomes, Defining and modulating the stress granule proteome as a therapeutic strategy in Amyotrophic Lateral Sclerosis, """Investigating autophagy enhancement as a therapeutic approach for the treatment of Rett syndrome. Global advisory DSS platform for citrus fruit growers, Connecting to the Networks of the Human Brain, Investigating the pharmacokinetic properties of toxic metals and heat shock proteins as risk factors in Amyotrophic Lateral Sclerosis, From co-transcriptional splicing kinetics to the evolutionary impact of exon and intron definition. AGLARIS: The First Fully-automated Bioreactor for Large Scale Human Stem Cell Production through an Iterative Process. Molecular Subtype Specific Stem Cell Dynamics in Developing and Established Colorectal Cancers, Origin and Protection of Unstable Repetitive DNA Elements During Sexual Reproduction, Next Generation Label-free Chemical Nanoscopy for Biomedical Applications, A systematic characterization of human regulatory architectures and their determinants of regulatory activity, Mechanisms of Gene Silencing by the Glucocorticoid Receptor. : 116072, Clearance Of Microbial Biofilms by Advancing diagnostics and Therapy, Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes, Faster magic-angle spinning leads to a resolution revolution in biological solid-state NMR, DEVELOPMENT OF HEALTHY HOST-MICROBIAL MUTUALISM IN EARLY LIFE, GENOTYPE - ENDOPHENOTYPE ASSOCIATIONS IN PSYCHOSIS, Biomedicine international training research programme for excellent clinician-scientists, Gene Editing as Therapeutic Strategy for C9ORF72 Linked ALS/FTD, Development of Tagged (DIVA), Virus-Like-Particle polyantigenic Vaccine against Bovine Viral Diarrhea virus (BVDc), Cloud collaborative open platform for advanced brain analytics. OncoSeq: an innovative single-cell system for immunomonitoring, Manufacturing and testing of an allogeneic gamma delta T cell therapy for the treatment of cancer, Non invasive Cell Based Liquid Biopsy Platform for Bladder Cancer, Non-invasive technology for remote screening and personalised therapy of sleeping disorders: EU piloting and commercialisation project, Revolutionary opto-biological methodology for aggressive HER2 cancer, Natural Food formulation for the prevention and treatment the Obesity and Metabolic Syndrome obtained with herbal extracts, The N-IF mouse – a new and unique fibrosis model for preclinical efficacy studies, The first simple monitoring device for Parkinson and other Tremor diseases. A microfluidic cryofixation method for time-resolved correlative microscopy, Circadian Control of Histone Methylation Dynamics through the Fine-tuning of Methionine Metabolic Flux, Muscle Specific C. elegans Genome in health and disease: finding novel factors in 3D organization, Maternal Obesity and Epigenetic Reprogramming: from Gametogenesis to Early Embryonic Development, Fusarium oxysporum mediated underpinning of cell type-specific modulation in multiple host interaction, Towards a molecular understanding of the centriole assembly process, Patient specific magnetic resonance image guided biomechanical modelling of the heart – Anovel tool towards personalized medicine in heart failure, A LAB-ON-A-CHIP DEVICE FOR PURE CIRCULATING TUMOR CELL ISOLATION FROM WHOLE BLOOD FOR CANCER THERAPY, Comprehensive analysis of yeast expression-fitness functions (EFFs), Long range-acting drivers of premetastatic niches in melanoma, Communication strategy and tools for optimizing the impact of Ebola vaccination deployment – Sofia ref. Optical imaging platform to unravel metabolic reprogramming of cancer: a path for improved treatments, Revealing the contribution of liver macrophage populations to NASH in insulin resistance, SMART MICROBIOME-BASED PLATFORM FOR THE EARLY DETECTION OF BIOLOGICAL THREATS IN AGRICULTURE, 3-D Super resolution Ultrasound Real time imaging of Erythrocytes, Deciphering the niche adaptations of a gut commensal involved in educating the host immune system, Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease, A new translational strategy for tailored treatment of type 2 diabetes, Prevention of childhood Acute Lymphoblastic Leukemia immunology links oncology, Molecular mechanisms of presynaptic plasticity, Three-dimensional dynamic views of proteomes as a novel readout for physiological and pathological alterations, MRI toolkit for in vivo fat virtual biopsy, Ruthenium-based photoactivated chemotherapy against eye cancer, New vaccine for a paradigm shift in Brucellosis, one of the world’s most widespread zoonotic diseases affecting humans, The Oligo-Vascular interface: understanding its properties and functions, Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy, Ligand Directed NIR-based Theranostic Prodrugs for Prostate Cancer, Cell type-specific molecular analysis of epigenetic changes and transposable element derepression in Alzheimer's disease progression, Dynamic proteomic maps of stem cell-derived neurons as a mechanistic discovery pipeline for rare neurological disease, Hippocampus Extracellular Space Simulator Project (HESSP), Elucidating transcriptional rewiring on hematological malignancies via computational methods, Characterizing the roles of transcription factor isoforms in rewiring gene regulatory networks during adipogenesis. 3D Liver Organoids: Modelling Host Hepatitis B Virus Interaction. Dynamic Complexes and Allosteric Regulation of Small Molecule Transporters, An effective and safe targeted therapy for treatment of Myasthenia gravis, Navigating lymphatic formation and function in health and disease, Deciphering and predicting the evolution of cancer cell populations, Hepatocytes-Like Microreactors for Liver Tissue Engineering, Clinical assessment of PILA PHARMA’s TRPV1 antagonist, XEN-D0501, as a novel type of oral anti-diabetic agent, Ser-Col; from finger to laboratory; personalized and automated serum collection for laboratory diagnostics, Disease Risk And Immune Strategies In Social Insects, Enteric-nervous-system-mediated regulation of intestinal inflammation, Development of lipid nanoparticles based on solid matrix for Benznidazole oral delivery targeting to the lymphatic system to treat Chagas disease, The core and effects of epilepsy: from chronic disease to curable disorder through innovative guided surgery, Bioengineering lung tissue using extracellular matrix based 3D bioprinting, Advancing osteoporosis medicine by observing bone microstructure and remodelling using a four-dimensional nanoscope, Innovative Network for Next Generation Training and Sequencing of Virome, Apoptotic foci: composition, structure and dynamics, Exploring the Epigenome by Multiplexed Physical Mapping of Individual Chromosomes, spontaneous Evolution and Clonal heterOgeneity in MoNoclonal Gammopathies: from mechanisms of progression to clinical management, Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis, Therapeutic Allele Engineering: A novel technology for cell therapy, Identifying spatial determinants of immune cell fate commitment, Regulation of Brain Macrophage Development and Function, Infinite Protein Self-Assembly in Health and Disease, Decoding interactions between adipose tissue immune cells, metabolic function, and the intestinal microbiome in obesity, Brain cell type-specific interactions and schizophrenia, A unified drug discovery platform for protein misfolding diseases, PanCareFollowUp: Novel, patient-centred survivorship care to improve care quality, effectiveness, cost-effectiveness and accessibility for survivors and caregivers, REACH: Russian European Alliance for research among women, Children and adolescents impacted by HIV, TB and HCV, Project on Exercise for Fatigue Eradication in Advanced Breast cancer to improve quality of life, Living well, dying well. Bio-conjugatable and Bio-responsive Near Infrared Fluorochromes. Matrix glycans as multifunctional pathogenesis factors and therapeutic targets in cancer, Wrist and arm sensing technologies for cardiac arrhythmias detection, Next generation single molecule protein fluorescence, Organ-specific mechanisms of lymphatic vascular development and specialisation, Striatal cholinergic cell assemblies in movement disorders, Site-directed RNA Editing to Manipulate RNA and Protein Function, Chromatin dynamics during DNA replication. The therapeutic potential of Genipin as a corneal cross-linking agent: Unlocking a new pathway for the treatment of corneal infection and disease. Impact of vector-mediated transmission on the evolution and ecology of a bee virus, Individual differences in facial expressivity: Social function, facial anatomy and evolutionary origins, Mechanisms of Microglia Synapse Communication, Targeting leukaemia by modulating hematopoietic stem cell competitiveness, The molecular basis and genetic control of local gene co-expression and its impact in human disease, Engineered nanocarriers for simultaneous anticancer immune response and “switching” of tumor-associated macrophages for intranasal glioblastoma treatment, Cross-linking Adenosine Receptors - Estrogen receptors for OA treatment, Unraveling the Molecular Changes that Drive the Repression of the Unfolded Protein Response with Ageing. A novel muscle disorders 3D in vitro system for drug screening and validation. Non-histone protein acetylation targets of KAT2A in AML, Human Lung Microbiota And Innate Immunity. Follow your scientific passion and join us tonight on Researchers’ Night. Personalized Prevention for Coronary Heart Disease, mesoscale multi-mode MRI of molecular targets, Effective and Affordable Flu Vaccines for the World, Novel Strategies for Cell-based Neural Reconstruction, PRECISION MANUFACTURING OF MICROENGINEERED COMPLEX JOINT IMPLANTS. Next Generation instrument for in-depth mitochondrial status analyses, Osmotic Wearable Bolus Injector (oWBI) for viscous drug delivery, PulseHaler: Improving the Lives of COPD Patients, Novel human neurodegenerative disease specific 3D cell-models with applications in drug development and toxicity testing, An ICT decision support system for clinical interpretation of genomic data, used by geneticists to rapidly and accurately pinpoint unique disease-causing variants, De- and reconstructing virulence strategies of fungal plant pathogens, Transferring autonomous and non autonomous cell degeneration 3D models between EU and USA for development of effective therapies for neurodegenerative diseases (ND), Development of a tool kit to investigate protein ubiquitylation in biomedical research, Structural and functional characterization of the ICOS/ICOSL immune complex, Accurate assessment of thrombosis risk in systemic lupus erythematosus, Online and automated E. coli monitoring for 100% safe drinking water. Benefits under the Graco Employee Retirement Plan (“Retirement Plan”) consist of a fixed benefit which is designed to provide retirement income at age 65 of 43.5% of average monthly compensation, less 18% of Social Security-covered compensation (calculated in a life … Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil, Fermentation And behaviour of carbohydrates in the colon, Platelet tractions through the Glycoprotein (GP) GPIb receptor as a potential marker for platelet reactivity, TARGETING ENDOTHELIAL CELL AND CANCER AMOEBOID MOVEMENT TO OVERCOME RESISTANCE TO ANTI-VEGF AND ANTI-PROTEASE THERAPIES. Decoding impairments of gait and balance from local field potentials in patients with Parkinson's disease. Automated Mechanical Peripheral Stimulation for motor rehabilitation in people living with Parkinson’s Disease (PD), New vaccine for a paradigm shift in Brucellosis, Personalised Pancreatic Cancer Vaccination Therapy derived from Autologous Tumor Cells and Neoantigens. Intragranullar calcium regulation of mucin secretion and sorting. Immunohistochemistry identified a strong positivity for PD-L1 (70%). Molecular basis of human enhanceropathies, International NETwork for training and innovations in THErapeutic RADiation, Multi-omics Interdisciplinary Research Integration to Address DEmentia diagnosis, The life cycle of extracellular vesicles in prostate cancer: from biogenesis and homing, to functional relevance. A novel pharmaceutical treatment for nonalcoholic fatty liver disease, Retooling plant immunity for resistance to blast fungi, A metabolism-based prognostic biomarker for prostate cancer, Treatment of liver disease and cancer prevention. Targeting epigenetic demethylases: development of covalent inhibitors and PROTACs (Proteolysis Targeting Chimeras). The interoceptive link between anxiety and breathing perception, Role of Aβ Specific Regulatory T cells in harnessing cerebral Aβ clearance in Alzheimer’s Disease, Effects of major histocompatibility complex immunogenetic profiles of wild hybrid and non-hybrid marmosets on their susceptibility to arbovirus infections, Mechanically tuned Lung-on-a-Chip device to model pathology and drug screening for lung disease, UNDERSTANDING TRITROPHIC INTERACTIONS: PLANT-MICROBE-INSECT. A joint doctoral program to educate tomorrow’s insect pathologists: Solving disease problems in the upcoming insect rearing industry. Connectivity, plasticity and function of an olfactory memory circuit, A new innovative method for diabetes treatment, the artificial pancreas system, Super-resolution genomic mapping for the microbiome, Advanced Solutions for High Sensitivity Metabolism and Toxicity Assays, New MilliDrop Analyzer: miniaturized and faster clinical microbiology testing in only one drop, Developing Smart 3D Scaffolds based on Conductive Polymers and Carbon Nanotubes for Cardiac Tissue Engineering, Neuroimmune activation as a novel therapeutic approach for IBD, Development of a policy to stop the suffering caused by Nodding Syndrome and Onchocerciasis associated epilepsy, Assay for cancer diagnostics by quantification of 5hmC, PoC in-office device for identifying individuals at high risk of Osteoporosis and osteoporotic fracture, Mapping the retrotransposon-mediated layer of neuronal gene regulation in the human genome, Scalable inference algorithms for Bayesian evolutionary epidemiology, Affordable, accessible and automatic screening solution for diabetic retinopathy, The cryptic path of tumor-microenvironment interactions in prostate cancer, Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T CellRepertoire, From Typhoid Fever to Antimicrobial Mechanisms, The best online drug discovery platform, Building the Ultimate chemical database for drug discovery, Lubricating Cartilage: exploring the relation between lubrication and gene-regulation to alleviate osteoarthritis, Translational implications of the discovery of brain-draining lymphatics, Centre of Excellence in Digital Health and Personalised Medicine, Point-of-care device based on KETs for diagnosis of food allergies, Telemetric control of oxygen delivery for therapy optimization and adherence, Treatment against honeybee varroosis based on highly effective application of oxalic acid through sublimation. 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